Qiang, J. Ding, Y. Emma, P. Huang, Z. Ratner, D.F. Raubenheimer, T.O. Zhou, F. JACoW Geneva, Switzerland 978-3-95450-180-9 10.18429/JACoW-NAPAC2016-WEPOB30 English 967-970 WEPOB30 ion simulation laser electron bunching Contribution to a conference proceedings 2017 2017-01 http://dx.doi.org/10.18429/JACoW-NAPAC2016-WEPOB30 https://jacow.org/napac2016/papers/wepob30.pdf The shot-noise driven microbunching instability can significantly degrade electron beam quality in next generation light sources. Experiments were carried out at the Linac Coherent Light Source (LCLS) to study this instability. In this paper, we will present start-to-end simulation of the shot-noise driven microbunching instability experiment at the LCLS.