González, N. Colldelram, C. Crisol, A. Garriga, D. Juanhuix, J. Nicolàs, J. Quispe, M. Šics, I. JACoW Publishing Geneva, Switzerland 2673-5520 978-3-95450-250-9 10.18429/JACoW-MEDSI2023-TUOAM04 English 5-9 detector optics synchrotron cryogenics experiment Contribution to a conference proceedings 2024 2024-07 https://doi.org/10.18429/JACoW-MEDSI2023-TUOAM04 https://jacow.org/medsi2023/papers/tuoam04.pdf The new BL06-XAIRA microfocus macromolecular crystallography beamline at ALBA synchrotron is currently under commissioning and foreseen to enter into user operation in 2024. The aim of XAIRA is to provide a 4-14 keV, stable, high flux beam, focused to 3×1 µm2 FWHM. The beamline includes a novel monochromator design combining a cryocooled Si(111) channel-cut and a double multilayer diffracting optics for high stability and high flux; and new mirror benders with dynamical thermal bump and figure error correctors. In order to reduce X-ray parasitic scattering with air and maximize the photon flux, the entire end station, including sample environment, cryostream and detector, is enclosed in a helium chamber. The sub-100nm SoC diffractometer, based on a unique helium bearing goniometer also compatible with air, is designed to support fast oscillation experiments, raster scans and helical scans while allowing a tight sample to detector distance. The beamline is also equipped with a double on-axis visualization system for sample imaging at sub-micron resolutions. The general status of the beamline is presented here with particular detail on the in-house fully developed end station design.