Geraldes, R.R. JACoW Publishing Geneva, Switzerland Sirius is a fourth-generation synchrotron light source that has been operational since 2020 at the Brazilian Synchrotron Light Laboratory (LNLS). Initial funding covered a total of 14 beamlines, six of which are currently open for users, and eight under commissioning or assembly, due in 2024. In a subsequent phase, 13 more beamlines are expected for the coming years. Thanks to the reduction in source sizes and the increase in brightness and coherence properties, new-generation synchrotrons open unprecedented research opportunities, pushing beamline instrumentation up for performance. This can often translate to requirements such as superior mechanical stability, more advanced motion options, faster and higher-resolution detectors, and larger computing power. This talk reviews Sirius’s main nanopositioning and optical beamline systems, summarizing the current engineering framework, providing lessons learned, and discussing future opportunities.