Jeangerard, D. Ciccone, L. Desjardins, D.K. Haouz, A. Le Jollec, A. Savko, M. Shepard, W. E. JACoW Publishing Geneva, Switzerland 978-3-95450-207-3 10.18429/JACoW-MEDSI2018-WEPH36 English 283-285 WEPH36 experiment synchrotron detector GUI instrumentation Contribution to a conference proceedings 2018 2018-12 https://doi.org/10.18429/JACoW-MEDSI2018-WEPH36 http://jacow.org/medsi2018/papers/weph36.pdf PROXIMA 2A is a high performance 3rd generation synchrotron beamline dedicated to X-ray micro-crystallography on biological macromolecules. Since opening in March 2013, the experimental station has hosted a large number of users who have collected vast amounts of X-ray diffraction images from literally thousands of crystals. In order to streamline the throughput, enhance performance and add functionality, a number of innovative developments have been launched on PROXIMA 2A. These cover all aspects of the beamline, from the practical to the visionary: such as the design, fabrication and implementation of a dedicated high-precision motorized stage to screen crystallization plates for in situ X-ray data collections, and the employment artificial intelligence and computer vision technologies for the detection of samples under liquid nitrogen. Other notable beamline projects include the addition of a vertical translation table for the EIGER X 9M detector to permit the acquisition of ultrahigh (0.6 Å) resolution X-ray data, the incorporation of a miniaturized YAG-coupled photodiode within a beamstop and the determination of the SOC of a recently added kappa arm to the goniometer.