Taghibi Khotbeh-Sara, A. Ghasemi, F. Khalafi, H. Mohseni Kejani, M. Rahmani, F. JACoW Publishing Geneva, Switzerland 2226-0366 978-3-95450-194-6 10.18429/JACoW-LINAC2018-MOPO069 English 148-150 MOPO069 target photon electron neutron linac Contribution to a conference proceedings 2019 2019-01 https://doi.org/10.18429/JACoW-LINAC2018-MOPO069 http://jacow.org/linac2018/papers/mopo069.pdf Today providing enough supplies of 99mTc / 99Mo as a high usage radioisotope in diagnostic nuclear medicine for the world demand is a big challenge. One of the proofed ways to access reliable source of this radioisotopes is production using e-LINAC [1]. In this investigation it was tried to find the simple and the optimized design of 99Mo production target based on photoneutron reaction using e-LINAC. Based on the Monte-Carlo calculation for radiation transport and finite element thermal analysis, 9 thin plates of enriched 100Mo was suggested. Equal distance between plates was considered for cooling to prevent target melting. The main target includes only 100Mo in one-stage approach method to increase production rate in compare with two-stage approach [2]. Applying 2.5 m/s for inlet velocity of cooling water provides suitable cooling process with maximum temperature of target about 900 ˚C.