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| URL | https://doi.org/10.18429/JACoW-IPAC2025-TUPB048 |
|---|---|
| Title | Installation, operations, and upgrade of a CS-30 cyclotron for the production of alpha emitters At-211 and Ac-225 at the Ionetix TAT facility |
| Authors |
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| Abstract | Ionetix Corporation has been conducting research and development on compact superconducting cyclotrons for medical isotope production, with multiple Ion-12SC units installed and operated at customer sites in USA. Since 2021, we have also focused on the production of alpha-emitting medical isotopes for cancer therapy, specifically At-211 and Ac-225. As a first step, Ionetix acquired an existing, partial CS-30 Cyclotron system decommissioned and stored in a warehouse. We refurbished and upgraded the CS-30 cyclotron, replacing components as needed. The installation of the CS-30 was completed in 2022, and it has been operational, accelerating alpha and proton beams since 2023. The refurbished cyclotron features new main and trim coils, a new internal bismuth target and drive, and a new central region to enhance the beam-on-target performance. All power supplies, controls, and instrumentation were replaced with commercially available components. The first production of At-211 at Ionetix was achieved in April 2023, followed by the first production of Ac-225 in June 2024. This paper analyzes and describes the CS-30 cyclotron, and the upgrades and enhancements developed at Ionetix. |
| Paper | download: TUPB048.pdf |
| Cite | BibTeX, LaTeX, Text/Word, RIS, EndNote |
| Conference | 16th International Particle Accelerator Conference |
| Series | |
| Location | Taipei, Taiwan |
| Date | 01-06 Jun 2025 |
| Publisher | JACoW Publishing, Geneva, Switzerland |
| Editorial Board | * Ming-Chyuan Lin - National Synchrotron Radiation Research Center * Yoichi Sato - KEK * Jui-Che Huang - National Synchrotron Radiation Research Center * David Button - Australian Nuclear Science and Technology Organisation * Ping-Shun Chuang - National Synchrotron Radiation Research Center |
| Online ISBN | 978-3-95450-248-6 |
| Online ISSN | 2673-5490 |
| Received | 28 May 2025 |
| Revised | 04 June 2025 |
| Accepted | 05 June 2025 |
| Issued | 05 November 2025 |
| DOI | 10.18429/JACoW-IPAC2025-TUPB048 |
| Pages | 1075-1078 |
| Copyright | Published by JACoW Publishing under the terms of the Creative Commons Attribution 4.0 license. Any further distribution of this work must maintain attribution to the author(s), the published article's title, publisher, and DOI. |