THPM002

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URL	https://doi.org/10.18429/JACoW-IPAC2025-THPM002
Title	VHEE FLASH radiotherapy: cutting-edge research at CLEAR, the CERN Linear Electron Accelerator for Research
Authors	P. Korysko University of Oxford A. Malyzhenkov, A. Gilardi, L. Wroe, R. Corsini, V. Rieker, W. Farabolini European Organization for Nuclear Research H. Kacem, J. Ollivier, M. Vozenin University Hospital of Geneva L. Kunz University of Geneva M. Dosanjh European Organization for Nuclear Research, University of Oxford
Abstract	With the current availability of cost-effective and compact electron LINACs operating in the 100-200 MeV energy range, there has been a growing interest in using Very High Energy Electron (VHEE) radiotherapy (RT) for cancer treatment. A particularly intriguing aspect is the Ultra High Dose Rate (UHDR) or FLASH dose regime, which focuses on damaging cancerous cells while sparing healthy tissues. VHEE beams are well-suited for FLASH RT, given their deep penetration and high beam current, making them effective for treating large, deep-seated tumors. The CLEAR (CERN Linear Electron Accelerator for Research) facility has been at the forefront of exploring VHEE and FLASH RT, conducting numerous unique experiments in collaboration with multidisciplinary user groups having experience in dosimetric, chemical, and biological studies. This paper introduces recent measurements, techniques, and methods used to observe the FLASH effect at CLEAR.
Paper	download: THPM002.pdf
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Conference	16th International Particle Accelerator Conference
Series
Location	Taipei, Taiwan
Date	01-06 Jun 2025
Publisher	JACoW Publishing, Geneva, Switzerland
Editorial Board	* Ming-Chyuan Lin - National Synchrotron Radiation Research Center * Yoichi Sato - KEK * Jui-Che Huang - National Synchrotron Radiation Research Center * David Button - Australian Nuclear Science and Technology Organisation * Ping-Shun Chuang - National Synchrotron Radiation Research Center
Online ISBN	978-3-95450-248-6
Online ISSN	2673-5490
Received	27 May 2025
Revised	02 June 2025
Accepted	03 June 2025
Issued	05 November 2025
DOI	10.18429/JACoW-IPAC2025-THPM002
Pages	2691-2694
Copyright	Published by JACoW Publishing under the terms of the Creative Commons Attribution 4.0 license. Any further distribution of this work must maintain attribution to the author(s), the published article's title, publisher, and DOI.